Simplified Cell Sorting with SH800S: A Comprehensive Solution for Diverse Research Needs
In the fast-paced world of cell biology, the ability to sort cells with precision and efficiency is crucial for advancing research. The SH800S Cell Sorter, a benchtop system designed with cutting-edge technology, offers researchers unparalleled flexibility and ease of use. Whether you’re working in an individual lab or a core facility, the SH800S adapts to a wide range of applications, making cell sorting more accessible and less complex.
Advanced Microfluidic Chip Technology
At the heart of the SH800S is its innovative microfluidic sorting chip, which comes in three sizes: 70 μm, 100 μm, and 130 μm. This versatility allows researchers to sort cells of varying sizes, catering to the specific requirements of different experiments. The chip-based design integrates seamlessly with the system’s fluidics controls, ensuring precise and consistent results. With the SH800S, the days of subjective and error-prone sorting are over. The system automates key steps, from setup to analysis, providing a level of precision that manual methods simply can’t match.
Intuitive System Software
The SH800S’s software is designed with the user in mind, featuring an intuitive interface that simplifies the entire sorting process. Researchers can sort cells into tubes, 96-well plates, or even 384-well plates with ease. The software supports the export of FCS 3.0 and FCS 3.1 files, which can be analyzed using third-party tools, ensuring that data can be easily integrated into existing workflows. The system’s flexibility is further enhanced by the option to use e-beam sterilized consumables, which replace the sample line and sorting chip, reducing the risk of cross-contamination—an essential feature for applications where sterility is paramount.
Comprehensive Biosafety Solutions
Safety is a top priority in any lab, and the SH800S addresses this with an optional Class A2 Level II biosafety cabinet. This cabinet, custom-designed for the SH800S, has been rigorously tested by The Baker Company to meet international biosafety standards, providing protection for both personnel and samples. This integration ensures that the SH800S can be used in a wide range of environments, including those where biohazardous materials are handled.
Flexible Optical Design for Diverse Applications
The optical design of the SH800S is another standout feature, offering up to four collinear excitation lasers (488 nm, 405 nm, 561 nm, and 638 nm) and six fluorescence detectors. This configuration allows for the detection of a broad range of fluorescence signals, giving researchers the flexibility to design experiments according to their specific needs. The six free-form PMTs enable the detection of signals from any laser, based on the selected filters, providing further customization options.
Unmatched Automation and Ease of Use
One of the most significant advantages of the SH800S is its high level of automation. Researchers can set up, calibrate, and monitor the system with just the push of a button, streamlining the workflow and reducing the potential for human error. The system’s patented CoreFinder™ technology plays a critical role in this automation, guiding users through the process of loading the sorting chip, selecting lasers, and inserting the required optical filters. The fluidics check ensures that the system is ready for operation, and the auto-calibration feature aligns the sorting chip with the lasers, calibrates the droplets, and estimates the drop delay using AutoSetup beads.
User-Friendly Data Analysis
Data analysis is a crucial aspect of cell sorting, and the SH800S makes this process straightforward. Data is displayed as dot plots and histograms, allowing researchers to gate events and mark target populations easily. The software provid
