iMSPR-Pro SPR system

Automated sustainable SPR system for drug discovery and precise kinetics

Pro series common features

Sample to Answer

After designing an experiment through the Experiment Wizard, when a sample is injected, the kinetics evaluation value can be obtained through the automatic analysis function built into the iMSPR operating software.

Sustainable U-type fluidics module

Through the U-type fluidics module, the immobilization step can be shortened efficiently, and referencing can be performed perfectly without time lag. In addition, it can be used permanently since it is manufactured with a PEEK unibody.

 

Inlet 2

When using both channels (binding analysis)

Inlet 1

When immobilizing the ligand

Outlet

Automatic qualification check of sensor chip

The sensor chip status is checked before the experiment through the automatic check function built into the iMSPR operation software. You can secure more reliable data by checking initialization status.

 
 
 
 

In-line degassing system

If you use the iMSPR Pro series, degassing the buffer is unnecessary. The built-in degassing module reduces the failure rate of experiments by removing bubbles.

 
 
 

What are the differences between iMSPR Pro Series

.

Pro2X

ProX

Pro

Sample flow channel

4

two experiments per chip

4

one experiment per chip

2

one experiment per chip

Fluidics module

UFD Fluidics module with dual U-type flow cells

Standard Fluidics module with mono U-type flow cells

Standard Fluidics module with mono U-type flow cells

Sample injection

Autosampler with dual injection valve

48 vials rack x 2
96 well plate x 2

Autosampler with mono injection valve

48 vials rack x 2
96 well plate x 2

One by one

Sample volume (200ul sample loop)

Max 200ul Partial injection available 30 ~ 75 ul dead volume

Max 200ul Partial injection available 30 ~ 75 ul dead volume

Max 200ul Partial injection available 30 ~ 60 ul dead volume

Screening capacity

300 samples per day

150 samples per day

Not recommended

Add options, get powerful functions

Temperature control unit

In various temperature environments (10 to 40 degrees, room temperature dependent conditions), it is possible to obtain the value of the bonding properties and obtain the thermodynamic constants (enthalpy, entropy) through this. as well as biological temperatureThe binding properties of new drug candidates can be confirmed in the environment (37 degrees). Through this, predict the dynamics of the drug​ in the body and understand the bonding between molecules more completely.

Cooling unit

When a large amount of sample needs to be analyzed, drug candidates such as antibodies may be denatured due to the high temperature inside the autosampler. The cooling unit is a temperature cooling function inside the autosampler that can prevent this. It can cool down to 4 degrees, so you can safely analyze your samples until the end. 

GxP Program

21 CFR compliance compliant programs can be installed. 

Premium maintenance program

If you upgrade to iMcare+, a premium maintenance/management program, you can extend the warranty period to 2 years, as well as receive regular inspection, SW upgrade, free replacement of consumables and free operation training for 10 years.

 

Specifications

Pro2XProXPro
Common Includings

iMSPR-Pro main body (1 set), Prism holder (1ea), Detach tool (1ea), PC (1ea), SW (1cp), Flat tweezer (1ea), Matching oil (3ml), USB cable (1ea), Power cable (1ea)
Individual Includings
UFD Fluidics module with dual U-type flow cells (1ea), Autosampler with dual injection valve (1ea), 48 vial rack (1ea), Vials of 750ul (1pk)
Standard Fluidics module with mono U-type flow cells (1ea), Autosampler (1ea), 48 vial rack (1ea), Vials of 750ul (1pk)
Standard Fluidics module with mono U-type flow cells (1ea), Syringe of 250ul (1ea)
Waranty1 years
SPR type
Angular interrogation, Prism coupling
Light sourceNear IR LED
Detector2D CMOS image sensor (The detailed specification of each model is different.)
Association range
10³ to 10⁷ M⁻¹ s⁻¹
Dissociation range
10⁻⁵ to s⁻¹
Affinity range
10⁻³ to 10⁻¹² M⁻¹
Noise level
0.1 RU
Sample type
Small compounds, peptides, oligomers, lipids, proteins, cell-like molecules
DMSO resistance
10%

Resources

Ordering Information

Models
iMSPR-Pro2X 1 unit
iMSPR-ProX 1 unit
iMSPR-Pro 1 unit
Options
Temperature control unit 1 unit
Cooling unit (ProX/2X models only) 1 unit
Sensor chip storage Kit 1 kit
Software
TraceDrawer (Analysis program) 1 kit
GxP Program Standard 1 kit
GxP Program Customized 1 kit

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