Preparative HPLC systems and columns (Laboratory, Pilot and Process scale)

Hanbon offers preparative HPLC and MPLC equipment from laboratory to industrial scale, for purification of small molecules such as intermediates, APIs, insulin, peptides, natural products

Hanbon, as one of the leading HPLC system manufacturers, currently produces laboratory/pilot scale Newstyle prep-HPLC system models (NS) and industrial scale CS-Prep systems, as well as world-known prep-HPLC dynamic axial compression DAC columns for pilot and industrial scale applications.

Newstyle laboratory liquid chromatography systems were developed for laboratory analysis, small-scale and pilot scale up. The infusion pump head and liquid circuit contact materials can be selected from SS316L, titanium alloy, PEEK etc., which are suitable for the special requirements of different customers’ processes. Dual wavelength UV visible detector, which can expand the detection range, and can also be equipped with differential refractive detector or evaporative luminescence detector.

CS-Prep industrial preparative HPLC systems include infusion, injection, detection, distillate collection, control and data processing modules. This model became the first diaphragm pump explosion-proof industrial preparation liquid chromatography system in China, which achieved balance, sample loading, flushing, elution, automatic collection, online cleaning and other process.

In 2005 Hanbon developed the first dynamic axial compression column with independent intellectual property rights in China, and by nowadays has built the largest dynamic axial compression column production and assembly workshop in the world. Dynamic axial compression columns are automated self-packed and unpacked in place devices, have pressure control system and can totally satisfy the continuity of the column bed, uniformity, stability, and tightness requirements, eliminate the influence of the column bed collapse.

Hanbon production facility is based on the design and implementation process of GAMP 5; producer provides complete GMP and FDA verification documents and services.

The control software is based on the secondary development of imported workstations and meets the requirements of FDA 21CFR Part 11.

 

Specifications

Laboratory and pilot scale benchtop systems
NS4201 NS4205 NS4210 NS4330 NS4360 NS43100 NS43300
Feed pump type Infusion pump; electronic damping flow control technology; floating piston design.
Flow rate 0.001-10 ml/min 0.01-50 ml/min 0.01-100 ml/min 0.01-300 ml/min 0.01-600 ml/min 0.1-1000 ml/min 0.1-3000 ml/min
Maximum system pressure 42 MPa 25 MPa 20 MPa 15 MPa 15 MPa 10 MPa 10 MPa
Optical detector 190-700 nm, 2-channel
Injection Automated injection valve Pump injection
PC and software Control PC and EasyChrom software
Optional modules Sample pump, additional detectors (pH, conductivity, RID, diode-array, luminometer, etc.), autosampler, fraction collector, switch valves for fluid control automatization)
Industrial scale skids
CS-Prep 150/200 CS-Prep 300 CS-Prep 400/500 CS-Prep 600 CS-Prep 800/1000/1100 CS-Prep 1200 CS-Prep 1600
Feed pump type Diaphragm pump
Pump max flow 200 L/H 300 L/H 500 L/H 1200 L/H 2000/3000 L/H 5000 L/H 10000 L/H
Maximum system pressure 100 bar 70 bar
Optical detector Single wavelength, 2 wavelength, or 4 wavelengths (200-400nm or 190-700nm)
Pipeline 1/4″ / 3/8″ 1/2″ / 3/4″ 1″
Pipeline material ASTM A269 (SS316L)
Explosion-proof level ExdIIBT4
All the Industrial scale models are customized and should be configured in accordance with technical requirements. 

 

Resources

Ordering Information

Models (systems and columns)
NS4201 Newstyle HPLC system 1 unit
NS4205 Newstyle HPLC system 1 unit
NS4210 Newstyle HPLC system 1 unit
NS4330 Newstyle HPLC system 1 unit
NS4360 Newstyle HPLC system 1 unit
NS43100 Newstyle HPLC system 1 unit
NS43300 Newstyle HPLC system 1 unit
CS-Prep 150/200 Industrial preparative HPLC system 1 unit
CS-Prep 300 Industrial preparative HPLC system 1 unit
CS-Prep 400/500 Industrial preparative HPLC system 1 unit
CS-Prep 600 Industrial preparative HPLC system 1 unit
CS-Prep 800/1000/1100 Industrial preparative HPLC system 1 unit
CS-Prep 1200 Industrial preparative HPLC system 1 unit
CS-Prep 1600 Industrial preparative HPLC system 1 unit
DAC50 Dynamic axial compression prep-HPLC column (50 x 650 mm) 1 unit
DAC80 Dynamic axial compression prep-HPLC column (80 x 650 mm) 1 unit
DAC100 Dynamic axial compression prep-HPLC column (100 x 650 mm) 1 unit
DAC150 Dynamic axial compression prep-HPLC column (150 x 680 mm) 1 unit
DAC200 Dynamic axial compression prep-HPLC column (200 x 680 mm) 1 unit
DAC300 Dynamic axial compression prep-HPLC column (300 x 650 mm) 1 unit
DAC400 Dynamic axial compression prep-HPLC column (400 x 650 mm) 1 unit
DAC450 Dynamic axial compression prep-HPLC column (450 x 650 mm) 1 unit
DAC500 Dynamic axial compression prep-HPLC column (500 x 650 mm) 1 unit
DAC600 Dynamic axial compression prep-HPLC column (600 x 650 mm) 1 unit
DAC800 Dynamic axial compression prep-HPLC column (800 x 650 mm) 1 unit
DAC1000 Dynamic axial compression prep-HPLC column (1000 x 650 mm) 1 unit
DAC1100 Dynamic axial compression prep-HPLC column (1100 x 650 mm) 1 unit
DAC1200 Dynamic axial compression prep-HPLC column (1200 x 650 mm) 1 unit
DAC1600 Dynamic axial compression prep-HPLC column (1600 x 650 mm) 1 unit
All the models should be configured in accordance with technical requirements. 

Please contact us for further discussion.

 

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