Bio-Lab Chromatography System (Laboratory scale)

Bio-Lab is a low/medium pressure benchtop chromatography systems for purification of proteins and other target molecules; available in different configurations from lab to pilot scale.

Bio-Lab laboratory chromatography system is a highly efficient, fast, and reliable automatic chromatography device independently developed by Hanbon for the purpose of the rapid purification of biological molecules and complexes, such as viruses, Mabs, proteins, polypeptides and nucleic acids, in the scale from micrograms to grams. The system utilizes a modular design and intelligent software, combined with different specifications of chromatographic columns, to meet the purification requirements of various biological macromolecules in the laboratory.

 

All the models meet the GLP/GMP requirements, validation documentation (DQ/IQ/OQ) is providing with each system by default. Bio-Lab software conforms to GLP/GMP and FDA 21CFR Part11 requirements.

 

All the devices are configured according to the customer’s requirements basing on 4 main platforms: Bio-Lab 30 / 100 / 300 / 600.

 

Specifications

Bio-Lab 30 Bio-Lab 100 Bio-Lab 300 Bio-Lab 600
System pump Binary piston pump, PEEK, titanium alloy or 316 L stainless steel;

Pump head self-washing function prevents pollution and salting out;

Electronic pressure fluctuation compensation provides excellent gradient accuracy and repeatability

Sample pump Available as option; could be the same flow rate as system pump or different
Flow rate and pump pressure 0.01 – 30 ml/min;

≤30 MPa

0.01 – 100 ml/min;

≤20 MPa

0.01 – 300 ml/min;

≤15 MPa

1 – 600 ml/min;

≤5 MPa

Flow rate accuracy ±0,5%
Gradient mixer chamber 0.6 ml static; 2 ml dynamic available as option 2 ml dynamic 5/10 ml dynamic 15 ml dynamic
Optical detector -5 … 5 AU detection range, 2 mm flow cell

2-channel 190-700 nm detector as standard;

4-channel 200-800 nm detector available as option

Conductivity probe 1~999 mS/cm detection range, with integrated temperature probe
pH probe Available as option; 0-14 pH detection range
Pressure probe One probe after the system pumps; optionally available the probe after sample pump and probe after the column
Air sensors Optionally available; before the pumps / after the pumps before the column
Injection valve Automated, 7-channel
Automated switch valves Available as options: inlet valves (2, 4 and 8 channels), column valve (1, 3 and 6 channels), outlet valve (2, 4 and 8 channels)
Fraction collector Available as option; compatible with 2-, 15- and 50-ml tubes and deep-well microplates
PC and Software Control PC and Bio-Lab software

Resources

Ordering Information

Models
Bio-lab 30 1 unit
Bio-lab 100 1 unit
Bio-lab 300 1 unit
Bio-lab 600 1 unit
All the models should be configured in accordance with technical requirements. 

Please contact us for further discussion.

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